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KMID : 0359920080270010145
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Korean Journal of Nephrology
2008 Volume.27 No. 1 p.145 ~ p.148
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Acute Arsine (AsH3) Intoxication
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Kim Sun-Min
Kim Tae-Young
Lee Kwang-Sun
Kim Do-Hyoung
Lee Kyung-Eun
Lee Jeong-An
Oh Dong-Jin
Yu Suk-Hee
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Abstract
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The present report describes a case of arsine intoxication. A 36-year-old male technician who handled gas in a semiconductor laboratory was admitted with severe abdominal pain and dark-red-colored urine. He was exposed to arsine gas while changing a gas bomb, since he mistook an arsine bomb for another, a different kind of a bomb. About 30 minutes after exposure, he suffered colicky abdominal pain, nausea, vomiting and dizziness. He noticed gross hematuria one hour later. On hospital in-patient day 2, the 24 h urine arsenic level was >1,000 μg/day, and the serum arsenic level was 309.4 μg/L.
Since BUN/ creatinine level had risen to 33/2.0 mg/dL at this stage, a hemoperfusion was performed. And then hydration was used to maintain urine output at 2 mL/kg/h. His condition had improved, although he complained of a severe headache which was a neuropathic sequela of arsenic exposure. He was discharged with a normal blood arsine level. To our knowledge, this is the second report of arsine poisoning in Korea but somewhat different from the first case.
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KEYWORD
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Arsine, Intoxication, Hemolysis, Acute renal failure
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